HOLES IN THE GLYCAN SHIELD OF THE NATIVE HIV ENVELOPE ARE A TARGET OF TRIMER-ELICITED NEUTRALIZING ANTIBODIES

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

A major advance in the search for an HIV vaccine has been the development of a near-native Envelope trimer (BG505 SOSIP.664) that can induce robust autologous Tier 2 neutralization.Here, potently neutralizing monoclonal antibodies (nAbs) from rabbits immunized with BG505 SOSIP.664 are shown to recognize an immunodominant region of gp120 centered on

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Identification and characterization of CmPP2C31 playing a positive role in the abiotic stress resistance of Chinese chestnut via an integrated strategy

Chinese chestnut (Castanea mollissima Blume) is an important economic forest tree species and mainly cultivated in mountainous areas and wastelands, subjecting it to various abiotic stresses.The protein phosphatase 2C (PP2C) genes contributes largely to stress responses Heavy Duty Transport Wheelchairs in plants.However, the characteristics and fun

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